Correlation between suboptimal vitamin D concentration and secondary hyperparathyroidism in women with low-energy fracture

Background/Aim. Osteoporosis is the most common metabolic bone disorder worldwide characterized by decreased strength that predisposes to an increased fracture risk, especially in postmenopausal women. Today, over 25 million people, mainly women, suffer from this disorder. In addition genetic predispositions, hormonal disorders, lifestyle, and insufficient vitamin D levels blood are significant risk factors for occurrence of osteoporosis low-energy fractures. The aim our study was analyze incidence correlation between deficiency secondary hyperparathyroidism women different ages with Methods. This cross-sectional included 559 who were not previously treated osteoporosis. All clinically examined their anamnesis chronic illnesses, fractures, therapies taken. Height weight measured, body mass index (BMI) calculated. Risk osteoporosis, including concentration 25-hydroxyvitamin [25(OH)D] parathyroid hormone (PTH), measured. Vitamin defined as serum level 25(OH)D less than 30 ng/mL (75 nmol/L). Results. a total which fractures identified 102 Women older (63.69 ? 13.88 years) compared without (54.39 14.10 (p < 0.0005). Furthermore, BMI also higher (27.75 kg/m2) other group (26.49 0.025). Out 88 postmenopausal. frequent humerus radius 11.62% (65/559), followed femoral neck 7.15% (40/559), vertebrae 3.04% (17/559). A decrease mineral density (BMD) spinal sites observed but did have impact on incidence. PTH statistically Conclusion. all three types age, BMD, mechanical force during fall (estimated through BMI).